Antifungal and post-antifungal effects of chlorhexidine, fluconazole, chitosan and its combinations on Candida albicans

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Antifungal and post-antifungal effects of chlorhexidine, fluconazole, chitosan and its combinations on Candida albicans.

OBJECTIVE The aim of this work was to assess the antifungal and post-antifungal effects of chlorhexidine, fluconazole, chitosan and its combinations on virulence factors of Candida albicans. STUDY DESIGN Ten isolated strains of Candida albicans obtained from 10 patients with oral candidiasis and a collection strain of C. albicans were treated with antifungal agents in different concentrations...

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Antifungal activity of essential oils from Iranian plants against fluconazole-resistant and fluconazole-susceptible Candida albicans

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Study of Antifungal Synergism Effects of Chitosan with Thymol, Carvacrol and Isothiocyanate against Candida albicans

Background and Aim: Prevalence of drug resistance in Candida albicans hinders common treatments with conventional antifungal drugs. A stockpile of research is being done to discover novel antifungal drugs. Chitosan has emerged as a promising antimicrobial and biodegradable polymer with various medical applications. The significant antimicrobial potential of some of the secondary metabolites fro...

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Antifungal synergy of theaflavin and epicatechin combinations against Candida albicans.

New antifungal agents are required to compensate for the increase in resistance to standard antifungal agents of Candida albicans, which is an important opportunistic fungal pathogen that causes minor infections in many individuals but very serious infections in those who are immune-compromised. In this study, combinations of theaflavin and epicatechin are investigated as potential antifungal a...

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Effects of Chitosan on Candida albicans: Conditions for Its Antifungal Activity

The effects of low molecular weight (96.5 KDa) chitosan on the pathogenic yeast Candida albicans were studied. Low concentrations of chitosan, around 2.5 to 10 μ g·mL(-1) produced (a) an efflux of K(+) and stimulation of extracellular acidification, (b) an inhibition of Rb(+) uptake, (c) an increased transmembrane potential difference of the cells, and (d) an increased uptake of Ca(2+). It is p...

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ژورنال

عنوان ژورنال: Medicina Oral Patología Oral y Cirugia Bucal

سال: 2011

ISSN: 1698-6946

DOI: 10.4317/medoral.16.e23